Test:COVID-19 Antigen (Rapid)
Other Test Request Name:
  • Rapid Test COVID-19 Ag
  • SARS-CoV-2 Antigen
  • COVID-19 Ag Rapid Diagnostic Test (RDT)
  • COVID-19 Ag Rapid Test
  • SARS CoV-1 Ag Test
Test Composition:

Not applicable

Intended Use:
  • Used for qualitative detection of SARS-CoV-2 antigen (Ag) in human nasopharyngeal swab.
  • Used as an aid in the diagnosis of SAR-CoV-2 infection
Methodology:

Rapid immunochromatography

Laboratory Section:

Molecular Diagnostics

Special Instructions/Patient Preparations:
  • COVID-19 Antigen (Rapid) testing is most useful during the acute phase of the desease when the viral load is high, which is within 5 days after onset of symptoms, however, it is the doctor's prerogative to request when he deems necessary. Note: A doctor's request ismandatory.
  • Present a valid ID with picture to Reception and Sample Collectors:

 

SAMPLE COLLECTION:

1.For walk in patients,sample collection is available by schedule in selected branches. (Please check website for contact details and branches available for collection).

2.For Sample Collectors: Wear proper PPEs and practice safety procedures in handling specimens.

3. If the patient has a lot of mucous in his/her nose, this can interfere with the collection of cells. Patient should use a tissue to gently clean out visible nasal mucous before a swab is taken. Discard tissue used as biohazard waste.

Collection/Sample Container:

Extraction Tube of COVID-19 Ag Kit

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

Nasopharyngeal Swab

Alternative Specimen and Volume Requirement:

Not applicable

Specimen Stability 
  • Room Temperature (15-30'C) - 2 hours
  • Refrigerated Temperature (2-8'C) - Not acceptable
  • Freezer Temperature (-20'C or lower) - Not acceptable

          Note:Direct swab samples should be tested immediately after collection.

•   Room Temperature (15-25°C):

Room Temperature (15-30'C) - 2 hours

•   Refrigerated Temperature (2-8°C):

Not acceptable

•   Freezer Temperature (-20°C):

Not acceptable

Transport Temperature:
  • Transport sample to Laboratory ASAP at room temperature
Rejection Criteria:
  • Exceeded sample stability requirement
  • Improper labeled sample
  • Improper collection tube used
  • Sample other than nasopharygeal swab
  • Incorrect volume of buffer used
Running Day:

Daily

Cut Off Time:

6;00 PM

TAT/Releasing of Results:

ROUTINE:  4 hours after receipt of sample

STAT:         2 1/2 hours after receipt of sample

Reference Interval/Result Interpretation:

Negative result:The presence of onl the control line (C) and no test line (T) within thge result window indicates a negative result.

Comment:A negative test result does not eliminate the possibility of SAR-CoV-2 infection and should be confirmed by aMolecular assay. Consult your doctor.

Positive result:The presence of the test line (T) and the control line (C) within the result window, regradless of which line appears first, indicates a positive result.

Note:The presence of any test line (T), no matter how faint, indicates a positive result.

Comment:Results may be confirmed with aMolecular assay. Consult yur doctor.

Invalid result:If the control line (C) is not visible within the result window after performing the test, the result is considered invalid.

Limitations/Interferences:
  • Positive test results do not rule out co-infections with other pathogens.
  • For further information on immune status, additional follow -up testing using other laboratory methods is recommended.
  • Test results must be evaluated in conjunction with other clinical date available to the physician.
  • This COVI-19 Ag Rapid Test Device is not intended to detect from defective (N=non-infectious) virus during the later stages of viral shedding that might be detected by PCR moleculat tests.
Frequently Asked Questions (FAQs):

Q:What is COVID-19 Ag Rapid Test?

A:Anin vitrodiagnostics rapid test for qualitative detection of SARS-CoV-2 antigen (Ag) using nasopharyngeal swab as sample.

Q:How does a rapid antigen detection test for COVID-19 work?

A:One type of rapid diagnostic test detects the presence of viral proteins (antigens) expressed by the COVID-19 virus in a sample from the respiratory tract of a person. If the target antigen is present in sufficient concentration in the sample, it will bind to specific anitbodies fixed to a paper strip enclosed in a plastic casing and generate a visually detectable signal, typically within 30 minutes. The antigen(s) detected are expressed only when the virus is actively replicating: therfore, such tests are best used to identify acute or early infection.

Q:What is the sensitivity and specificity of this test?

A:Positive specimens post onset of symptoms or suspected exposure between 0-3 days has a snsitivity of 94.9% and 4-7 days has a sensitivity of 90.1%.Overall sensitivity: 91.4%; Specificity: 99.8%

Q.What is the difference between COVID-19 Antigen and COVID-19 RT-PCT test?

A.: COVID-19 Ag Rapid Test Device detects antigens produced by the virus while COVID-19 RT-PCR test detects the virus RNA.. COVID-19 Antigen RAPID test does not detect defective (non-infectious) virus during the later shedding that might be detected by RT-PCR molecular tests.

Related Words/Test:

2019-nCoV IgG/IgM Antibody Detection, Corona virus disease, SARS-CoV-2, Flu desease.

 

Test:Coxsackie B1-6 (Serum) / CSF
Other Test Request Name:

• Picornavirus

 

Test Composition:

Coxsackie Antibodies :

• B1

• B2

• B3

• B4

• B5

• B6

 

Intended Use:

Coxsackie B Virus can cause rashes, pharyngitis, meningitis and myocarditis.

Methodology:

Complement Fixation (CF)

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation necessary.

Collection/Sample Container:

Red or Gold Tube / Steril Container for CSF

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

3 mL Serum / 3 mL CSF

Alternative Specimen and Volume Requirement:Not Applicable
Specimen Stability  
•   Room Temperature (15-25°C):

7 Days

•   Refrigerated Temperature (2-8°C):

14 Days

•   Freezer Temperature (-20°C):

30 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:

• Hemolyzed specimen
• Markedly lipemic specimen
• Exceeded sample stability requirement
• Quantity not sufficient
• Improperly labeled specimen
• Improper collection tube used

Running Day:

Batch Running

Cut Off Time:

Friday 4:00 PM

TAT/Releasing of Results:

2 weeks after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:Not Applicable
Limitations/Interferences:

Culture does not usually support growth of coxsackie A viruses.

Frequently Asked Questions (FAQs):Not Applicable
Related Words/Test:

• Rhinovirus

• Echovirus group

• Foot and Mouth Syndrome (kawasaki)

NOTE:After testing, HPD stores samples at refrigerated temperature for 6 days. Additional tests may only be entertained within 6 days provided sample is still stable for the analyte requested.

 

Test:Coxsakie B1-6 (CSF)
Other Test Request Name:

Coxsakie B (1-6) Antibodies

Test Composition:

Coxsackie Antibodies B1, B2, B3, B4, B5, B6

Intended Use:

Used to aid in the diagnosis of Coxsackie virus infection

 

Methodology:

Complement fixation (CF)

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation necessary.

Collection/Sample Container:

Sterile Leak-Proof Container

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

2 mL CSF

Alternative Specimen and Volume Requirement:

Not Applicable

Specimen Stability  
•   Room Temperature (15-25°C):

24 Hours

•   Refrigerated Temperature (2-8°C):

7 Days

•   Freezer Temperature (-20°C):

28 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:
  • Quantity Not sufficient
  • Improperly labeled specimen
  • Improperly container used
Running Day:

Batch running

Cut Off Time:

Monday, 12:00 PM

 

TAT/Releasing of Results:

3 weeks after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Available upon request

Limitations/Interferences:

None Specified

Frequently Asked Questions (FAQs):

Q: How common is coxsackie B virus?

A:Coxsackie B infections are most common in children, but may occur in adults

Q: What are the manifestations for this virus?

A:Clinical manifestations include:

  • fever
  • aseptic meningitis
  • costochondritis
  • pharyngitis
  • myocarditis
  • splenomegaly
  • diarrhea
  • maculopapular non-pruritic rash

Q: How is Coxsackie B virus transmitted?

A:The Coxsackie B virus gains access to the body through the mouth by the fecal-oral mode of transmission. The virus may also spread through contact with infected mucosal secretions

Q: Is Coxsackie B virus contagious?

A:Coxsackieviruses are very contagious. They can be passed from person to person on unwashed hands and surfaces contaminated by feces. They also can be spread through droplets of fluid sprayed into the air when someone sneezes or coughs.

Related Words/Test:

Not Applicable

 

Test:Coxsakie B1-6 (Serum)
Other Test Request Name:

Coxsakie B (1-6) Antibodies

Test Composition:

Coxsackie Antibodies B1, B2, B3, B4, B5, B6

Intended Use:

Used to aid in the diagnosis of Coxsackie virus infection

Methodology:

Complement Fixation (CF)

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation necessary.

Collection/Sample Container:

Red or Gold Tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

3 mL Serum

Alternative Specimen and Volume Requirement:

Not Applicable

Specimen Stability  
•   Room Temperature (15-25°C):

24 Hours

•   Refrigerated Temperature (2-8°C):

7 Days

•   Freezer Temperature (-20°C):

15 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:
  • Hemolyzed specimen
  • Quantity Not sufficient
  • Markedly lipemic sample
  • Improperly labeled specimen
Running Day:

Batch running

Cut Off Time:

Monday, 12:00 PM

 

TAT/Releasing of Results:

3 weeks after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Available upon request

Limitations/Interferences:

None Specified

Frequently Asked Questions (FAQs):

Q: How common is coxsackie B virus?

A:Coxsackie B infections are most common in children, but may occur in adults

Q: What are the manifestations for this virus?

A:Clinical manifestations include:

  • fever
  • aseptic meningitis
  • costochondritis
  • pharyngitis
  • myocarditis
  • splenomegaly
  • diarrhea
  • maculopapular non-pruritic rash

Q: How is Coxsackie B virus transmitted?

A:The Coxsackie B virus gains access to the body through the mouth by the fecal-oral mode of transmission. The virus may also spread through contact with infected mucosal secretions

Q: Is Coxsackie B virus contagious?

A:Coxsackieviruses are very contagious. They can be passed from person to person on unwashed hands and surfaces contaminated by feces. They also can be spread through droplets of fluid sprayed into the air when someone sneezes or coughs.

Related Words/Test:

Not Applicable

 

Test:CYP2C19 Genotype
Other Test Request Name:

• CardioIQ®

• Clopidogrel

Test Composition:

Not applicable

Intended Use:

• This test detects variants in the CYP2C19 gene leading to altered enzyme activity and may require alternative treatments or altered drug dosage of a drug metabolized by CYP2C19 for optimal therapeutic response.

Methodology:

Allele-Specific Primer Extension • Polymerase Chain Reaction (PCR)

 

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation necessary.

Collection/Sample Container:

EDTA or Violet Tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

4 mL EDTA whole blood

Alternative Specimen and Volume Requirement:

Not applicable

Specimen Stability  
•   Room Temperature (15-25°C):

8 Days

•   Refrigerated Temperature (2-8°C):

8 Days

•   Freezer Temperature (-20°C):

30 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:

• Improperly labeled specimens
• Incorrect collection tube used
• Hemolyzed specimens
• Lipemic specimens
• Quantity not sufficient
• Specimen transported outside the required temperature.

Running Day:

Batch Running

Cut Off Time:

Monday, 12:00 PM

 

TAT/Releasing of Results:

14 days after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Available upon request

Limitations/Interferences:

None specified

Frequently Asked Questions (FAQs):

Not applicable

Related Words/Test:Not Applicable

 

Test:Cystatin C (w/ eGFR)
Other Test Request Name:

Not applicable

Test Composition:

   1. Cystatin - C

   2. Estimated GFR (CKD-EPI)

 
Intended Use:
  • Use to calculate for Estimated Glomerular Filtration Rate (e-GFR) which in turn helps Physicians assess how well a person’s kidney is working.Used when a previous test for  kidney function was inconclusive or needs to be confirmed.
  • Used for patients who are overweight, elderly, or patients who does not have the average muscle mass/weight (whether higher or lower). Cystatin C-based estimates for GFR are believed to be less influenced by muscle mass or diet than Creatinine-based estimates.
Methodology:
  • Cystatin C:Particle-Enhanced Turbidimetric Immunoassay (PETIA)
  • e-GFR:calculated based on CKD-EPI CYSTATIN C EQUATION (2012)
Laboratory Section:

Chemistry

Special Instructions/Patient Preparations:

No patient preparation required.

Collection/Sample Container:

Red or Gold tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

1-3 mL Serum

Alternative Specimen and Volume Requirement:

1-3mL Plasma (Li-heparin, Na-heparin, EDTA)

Specimen Stability  
•   Room Temperature (15-25°C):

2 Days

•   Refrigerated Temperature (2-8°C):

7 Days

•   Freezer Temperature (-20°C):

1 Month

Transport Temperature:

Transport specimen at 2°C – 8 °C (with cold packs).

Rejection Criteria:
  • Specimens that failed serum index (hemolyzed and lipemic)
  • Exceeded sample stability requirement
  • Quantity not sufficient
  • Improperly labeled specimen
  • Improper collection tube used
Running Day:

Tuesday and Friday

Cut Off Time:

Monday to Saturday: 6:00 PM

 

TAT/Releasing of Results:

ROUTINE: 4 hours after receipt of specimen/ arrival of messenger.

STAT: After 2½ hours from extraction/messenger arrival.

 
Reference Interval/Result Interpretation:

Cystatin C:

  • 0~49 Y/O Male: 0.31~0.79 mg/L
  • 0~49 Y/O Female: 0.40~0.99 mg/L
  • 50~999Y/O  Male: 0.41~0.99 mg/L
  • 50~999Y/O  Female: 0.40~0.99 mg/L

Estimated GFR:>60 mL/min/1.73m^2

Limitations/Interferences:
  • Bilirubin, conjugated: 66 mg/dL(1128.6 umol/L)
  • Bilirubin, unconjugated: 60 mg/dL (1026 umol/L)
  • Hemoglobin: 1000 mg/dL (10 g/L)
  • Intralipid: 1000 mg/dL (10 g/L)
  • Rheumatoid factor: 500 IU/mL (300 kU/L)
Frequently Asked Questions (FAQs):

Q: How is it used?

A: A Cystatin C test may be used as an alternative to creatinine and creatinine clearance to screen for and monitor kidney dysfunction in those with known or suspected kidney disease. It is most useful in special cases where creatinine measurement could be misleading. Examples are patients with liver cirrhosis, are very obese, are malnourished, practice a vegetarian diet, have amputated limbs, or have reduced muscle mass (elderly and children). Cystatin C is not affected by body mass or diet, and hence is a more reliable marker of kidney function than creatinine. Measuring cystatin C may also be useful in the early detection of kidney disease when other test results (eGFR, creatinine or urine albumin) may still be normal or borderline and an affected person may have few, if any, symptoms. In this case, the healthcare practitioner may want to confirm if chronic kidney disease is present by measuring cystatin c.

 

Q: What does the result mean?

A: A high level of cystatin C in the blood corresponds to a decreased glomerular filtration rate (GFR) and hence to kidney dysfunction. Since cystatin C is produced throughout the body at a constant rate and removed and broken down by the kidneys, it should remain at a steady level in the blood if the kidneys are working efficiently and the GFR is normal. Recent studies suggest that increased levels of cystatin C may also indicate an increased risk of heart disease, heart failure, and mortality.

 

Q: What are the limitations of Cystatin test?

A: Although cystatin C is less variable and less affected by age, body mass, and diet than creatinine in some individuals, it is not a perfect test and can be affected by a number of drugs and other medical conditions. Some studies have reported increased cystatin C levels associated with higher levels of C-reactive protein (CRP) or body mass index (BMI), hyperthyroidism, steroid use, malignant diseases, HIV/AIDS, rheumatic diseases, and certain metabolic conditions such as hyperhomocysteinemia (increased homocysteine). In addition, other studies suggest that cystatin C can be cleared by non-kidney pathways, such as in the gut, and that its levels tend to fluctuate among patients with kidney transplants.

 

Q: Can Cystatin C be measured in urine samples?

A: No. Unlike creatinine, cystatin C is reabsorbed from the glomerular filtrate and then metabolized in the kidneys. Under normal conditions, cystatin C is not found at detectable levels in the urine.

 

Related Words/Test:

BUN, Creatinine Clearance, Comprehensive Metabolic Panel, Basic Metabolic Panel, Urinalysis, Urine Protein to Creatinine Ratio, Urine Albumin and Urine Albumin/Creatinine Ratio, Renal Panel, Beta-2 Microglobulin

 

Test:Cysticercosis
Other Test Request Name:

Taenia

Test Composition:

Not Applicable

Intended Use:

An infection due to the ingestion of cysterci of the porcine tape worm (Taenia solium) characterized by the development of small cysts in muscle, subcutaneous, eye and brain tissue (40% of cases). The clinical picture is related to the number of cysterci present. Serological analysis gives a positive result in 50% of patients and can be useful for confirmation of a diagnosis proposed on the basis of imaging techniques or histological examination of biopsy material.

Methodology:

Enzyme-immunoassay

Laboratory Section:

Special Test 

Special Instructions/Patient Preparations:

No patient preparation necessary.

Collection/Sample Container:

Red or Gold Tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

3 mL Serum

Alternative Specimen and Volume Requirement:

Not Applicable.

Specimen Stability  
•   Room Temperature (15-25°C):

24 Hours 

•   Refrigerated Temperature (2-8°C):

7 Days 

•   Freezer Temperature (-20°C):

28 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:
  • Hemolyzed specimen
  • Quantity Not sufficient
  • Improperly labeled specimen
  • Markedly lipemic sample
Running Day:

Batch Running

Cut Off Time:

Tuesday and Friday, 12:00 PM

TAT/Releasing of Results:

2 weeks after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Available upon request

Limitations/Interferences:

None specified.

Frequently Asked Questions (FAQs):

Q: What is Cysticercosis?

A:Cysticercosis is  an infection caused by the larvae of the parasite Taenia solium. This infection occurs after a person swallows tapeworm eggs. The larvae get into tissues such as muscle and brain, and form cysts there (these are called cysticerci). When cysts are found in the brain, the condition is called neurocysticercosis.

Q: What is the relationship between human tapeworm and porcine (pig) cysticercosis?

A:Human get the tapeworm infection after eating raw or undercooked pork contaminated with cysts of T. solium. When swallowed the cysts pass through the stomach and attach to the lining of the small intestine the cysts develop into adult tapeworms over about two months.

Q: Where is the cysticercosis found?

A:Cysticercosis is found worlwide. Infection is found most often in rural areas of developing countries where pigs are allowed to roam freely and eat human feces and where hygiene practices are poor. Cysticercosis is rare in people who live in countries where pigs do not have contact in human feces. People can sometimes get  cysticercosis even if they have never traveled outside the country.

 

Related Words/Test:

Not Applicable. 

 

Test:Cystine (HPLC)
Other Test Request Name:

Not applicable

Test Composition:

Not applicable

Intended Use:

• Cystinuria is an autosomal recessive disease in which dibasic amino acids, including cystine, are excreted in excess.

Methodology:

Liquid Chromatography/Mass Spectrometry (LC/MS)

/ HPLC - High Performance Liquid Chromatography

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation.

Collection/Sample Container:

Plastic leak proof clean container

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

50 Ml Random Urine

Alternative Specimen and Volume Requirement:

Not applicable

Specimen Stability  
•   Room Temperature (15-25°C):

Not applicable

•   Refrigerated Temperature (2-8°C):

24 Hours

•   Freezer Temperature (-20°C):

60 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:

•Quantity not sufficient

• Received room temperature

•Improperly labeled specimen

• Improper urine collection

• with preservatives

Running Day:

Batch Running

Cut Off Time:

Friday, 4:00 PM

TAT/Releasing of Results:

14 Days after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Available upon request

Limitations/Interferences:

None specified.

Frequently Asked Questions (FAQs):

Not applicable

Related Words/Test:Not Applicable

 

Test:Cytology (Fluid)
Other Test Request Name:
  • Cytology
Test Composition:
  • Not applicable
Intended Use:
  • Used to aid in the diagnosis of cancer, but also helps in the diagnosis of certain infectious diseases and other inflammatory conditions
  • Used on samples of free cells or tissue fragments, in contrast to histopathology, which studies whole tissues.
Methodology:
  • Cytospin and Papanicolau Staining
Laboratory Section:
  • Histopathology
Special Instructions/Patient Preparations:
  • Fresh sample must be delivered at once to the laboratory. Refrigerate if delay is anticipated.
  • Label with two (2) patient identifiers
  • Complete the Histopathology Request form (HPD_F_258) or Histopathology Service Request Form (HPD_F_259)
Collection/Sample Container:
  • Clean, tightly sealed bottle
Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:
  1. CSF – 1.0 mL
  2. Urine cytology – 50.0 mL
  3. Other body fluids – 30.0 mL
Alternative Specimen and Volume Requirement:
  • Not applicable
Specimen Stability  
•   Room Temperature (15-25°C):
  • 1 Day
•   Refrigerated Temperature (2-8°C):
  • 7 Days
•   Freezer Temperature (-20°C):
  • Not applicable
Transport Temperature:
  • Transport specimens at 2°C to 8°C
Rejection Criteria:
  • Incomplete information in the Histopathology Request form (HPD_F_258) or Histopathology Service Request Form (HPD_F_259)
  • Improperly labeled specimens
  • Quantity not sufficient
  • Exceeded sample stability requirement.
Running Day:
  • Daily
Cut Off Time:
  • 7:00 PM
TAT/Releasing of Results:
  • 3 to 5 days after receipt of specimen (with reading/interpretation)
  • 1 day for Metro Manila clients and 2 days for Provincial clients (processing only)
  • Note: Additional 2 days may be necessary if specimen needs further evaluation and confirmation by another Pathologist.
Reference Interval/Result Interpretation:
  • Not applicable
Limitations/Interferences:
  • Not applicable
Frequently Asked Questions (FAQs):
  • Not applicable
Related Words/Test:
  • Cytology

 

Test:CytoPhiladelphia (Karyo)
Other Test Request Name:

Cytogenetics-Philadelphia (KARYOTYPING)

Test Composition:

Not Applicable

Intended Use:

For fertility work-up

NOTE:Identification of chrmomosome abnormalities in cells obtained from the given sample is limited to those observed on metaphase spreads prepared by routine cytogenetic processing and analysis standards. In addition, this method does not rule out other forms of genetic abnormalities like low level tissue mosaicisms, submicroscopic abnormalities and other molecular mutations that are not detectable given the the limit of resolution of this procedure. 

Methodology:

GTG-Banding

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:
  • No patient preparation necessary.
  • Need Diagnosis
  • Doctors Request 
  • Please call laboratory prior to extraction. 
  • For schedule  (SPECIAL TRIP) 
  • Send sample immediately to HPD Del Monte 
  • Time of extraction will be 6AM only. (BRANCHES WITHIN METRO MANILA) (specimen should be at Laboratory at exactly 7AM)
  • Time of extraction will be 3PM onwards (FOR PROVINCIAL BRANCHES) (specimen should be at Laboratory until 7AM)
Collection/Sample Container:

Sodium Heparin Tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

 3 Pcs of 4 mL Sodium Heparinized whole blood 

Alternative Specimen and Volume Requirement:

Not Applicable

Specimen Stability  
•   Room Temperature (15-25°C):

24 Hours

•   Refrigerated Temperature (2-8°C):

Not Applicable

•   Freezer Temperature (-20°C):

Not Applicable

Transport Temperature:

Transport specimen at 15°C ~25 °C (room temperature)

Rejection Criteria:
  • Improperly labeled specimens
  • Clotted specimens
  • Over-filled or Under-filled tube
  • Quantity not sufficient
  • Specimen stored and transported outside the required temperature
Running Day:

Monday to Friday

Cut Off Time:

Monday to Friday, 7:00 AM

TAT/Releasing of Results:

4 weeks after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Not Applicable

Limitations/Interferences:

None Specified

Frequently Asked Questions (FAQs):

Not Applicable

Related Words/Test:

Congenital disorders, Down syndrome

 

Test:D-Dimer
Other Test Request Name:

Fibrin Degradation Fragment
Fragment D-dimer

Test Composition:

Not Applicable

Intended Use:

Used as an aid when deep venous thrombosis and pulmonary embolism is suspected

Methodology:

Sandwich Complex

Laboratory Section:

Serology

Special Instructions/Patient Preparations:

 

Please note the date and time of collection on sample tube and request.

Note: If date and time of collection not indicated we will automatically proceed the test but a comment will be reflected on the result, “No date and time of collection provided”.

 

Collection/Sample Container:

Heparin (Green Top)

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

2mL Heparinized Whole Blood

Alternative Specimen and Volume Requirement:

Not applicable

Specimen Stability  
•   Room Temperature (15-25°C):

8 Hours

•   Refrigerated Temperature (2-8°C):

Unacceptable

•   Freezer Temperature (-20°C):

Unacceptable

Transport Temperature:

Transport specimen at 15-25°C (room temperature)

Rejection Criteria:
  • Exceeded sample stability requirement
  • In appropriate collection tube (wrong anticoagulant)
  • Volume of blood to anticoagulant is not proportioned (Underfilled/Overfilled)
  • Clotted samples.
  • Improperly labeled specimens
  • Quantity not sufficient
Running Day:

Daily

Cut Off Time:

Monday to Saturday
• 6:00 PM


Sunday
• 3:00 PM

TAT/Releasing of Results:

ROUTINE
• 3 hours after receipt of specimen/ arrival of messenger
STAT
• 1½ hours from extraction/messenger arrival

Reference Interval/Result Interpretation:

0.00~0.50 ug/mL

Limitations/Interferences:

• High doses of biotin ( i.e. >5mg/day) may affect results. Samples should not be taken until at least 8 hours following the last biotin administration.
• High concentrations of lipoic acid may yield lower measurement values.
• High concentrations of d-fragments as may appear under thrombolytic therapy may yield lower measurement values.

Frequently Asked Questions (FAQs):

Not Applicable

Related Words/Test:

Deep vein thrombosis (DVT) ,Pulmonary embolism (PE), Fibrin Degradation Fragment, Fibrin Degradation Products, FDP, PT and INR, PTT, Fibrinogen, Platelet Count

 

Test:Dengue (IgM/IgG)
Other Test Request Name:

•Dengue Blot

•Dengue Fever Antibodies

Test Composition:

• Dengue IgG
• Dengue IgM
 

Intended Use:

• Used for the detection of IgG and IgM to dengue virus to human serum or plasma
• Used as an aid in the presumptive diagnosis between primary and secondary dengue infection
• During primary infection, Dengue IgM antibodies may be detectable on the 3rd to 5th day of fever and may persist for 30-60 days. Dengue IgG antibodies may be detected during 14th day of fever and may persist for life.
• In Secondary infections, IgG rises within 1-2 days after the onset of symptoms and induce IgM response after 20 days of infection.

Methodology:

Solid Phase Immunochromatography

Laboratory Section:

Serology

Special Instructions/Patient Preparations:

No patient preparation necessary.

NOTE: It is recommended to test for both Dengue NS1 and Dengue IgG/IgM if patient is on the 3rd day and onwards after the onset of fever.

Collection/Sample Container:

Red or Gold tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

1-2mL Serum

Alternative Specimen and Volume Requirement:

1-2mL Plasma (EDTA, Heparin, Na Citrate)

Specimen Stability  
•   Room Temperature (15-25°C):

Not Specified

•   Refrigerated Temperature (2-8°C):

7 Days

•   Freezer Temperature (-20°C):

>2 Weeks

Transport Temperature:

Transport specimen at 2 – 10 °C (with cold packs)

Rejection Criteria:

• Contaminated and markedly lipemic serum
• Improperly labeled specimens
• Hemolyzed specimens
• Quantity not sufficient
• Specimen stored exceeded outside required stability

Running Day:

Daily

Cut Off Time:

Monday to Saturday
• 8:00 PM

Sunday
• 3:00 PM

TAT/Releasing of Results:

ROUTINE
• 3 hours after receipt of specimen/ arrival of messenger
STAT
• 1½ hours from extraction/messenger arrival

Reference Interval/Result Interpretation:

• Dengue IgG: NEGATIVE
• Dengue IgM: NEGATIVE

Limitations/Interferences:

• Serological cross-reactivity across the Flavivirus group (Dengue virus, St. Louis encephalitis, Japanese encephalitis, West Nile virus and Yellow fever virus) is common.
• A negative result does not preclude the possibility of an early infection of Dengue virus.

Frequently Asked Questions (FAQs):

Not Applicable

Related Words/Test:

Dengue fever; Breakbone fever, Dengue Fever Antibodies; Dengue Fever Virus, Dengue NS Antigen, Dengue Virus by PCR

 

Test:Dengue NSI (Qualitative)
Other Test Request Name:

• Dengue NS1 Antigen

• Dengue NS1

•Dengue Fever Virus

Test Composition:

Not Applicable

Intended Use:

• Used for the qualitative detection of acute phase of dengue infection
• NS1 antigen may be found in the sample of infected patients from the first day and up to the 5th day after the onset of fever.

Methodology:

Lateral Flow Immunochromatography

Laboratory Section:

Serology

Special Instructions/Patient Preparations:

No patient preparation necessary.

NOTE: It is recommended to test for both Dengue NS1 and Dengue IgG/IgM if patient is on the 3rd day and onwards after the onset of fever.

Collection/Sample Container:

Red or Gold tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

1-2mL Serum

Alternative Specimen and Volume Requirement:

1-2mL Plasma (EDTA, Heparin, Na Citrate)

Specimen Stability  
•   Room Temperature (15-25°C):

Not Specified

•   Refrigerated Temperature (2-8°C):

7 Days

•   Freezer Temperature (-20°C):

>7 Days

Transport Temperature:

Transport specimen at 2 – 10 °C (with cold packs)

Rejection Criteria:

• Contaminated and markedly lipemic serum
• Improperly labeled specimens
• Hemolyzed specimens
• Quantity not sufficient
• Specimen stored exceeded outside required stability

Running Day:

Daily

Cut Off Time:

Monday to Saturday
• 8:00 PM

Sunday
• 3:00 PM

TAT/Releasing of Results:

ROUTINE
• 3 hours after receipt of specimen/ arrival of messenger
STAT
• 1½ hours from extraction/messenger arrival

Reference Interval/Result Interpretation:

NEGATIVE

Limitations/Interferences:

Samples from pregnant women or rheumatoid factors or anti-nuclear antibodies may yield positive results. A negative test result cannot exclude a recent infection.

Frequently Asked Questions (FAQs):

Not Applicable

Related Words/Test:

Dengue fever, Breakbone fever, Dengue Fever Antibodies; Dengue Fever Virus, Dengue Antibodies (IgG, IgM); Dengue Virus by PCR

 

Test:Dengue Virus RNA (PCR)
Other Test Request Name:

Dengue Virus RNA Qualitative

Test Composition:

Dengue Virus 1 or 3 RNA

Dengue Virus 2 or 4 RNA

Intended Use:

Dengue Virus RNA, Qualitative, Real-Time PCR - PCR is used to diagnose Dengue fever infection during the initial stage of infection, days 1-5 after onset of symptoms. The assay has been designed to detect dengue virus subgroups 1 and 3 (DV1/3 probe), as well as subgroups 2 and 4 (DV2/4 probe).

Methodology:

Real-Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation necessary

Collection/Sample Container:

Gold or Red tube

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

3mL Serum

Alternative Specimen and Volume Requirement:

Not Applicable

Specimen Stability  
•   Room Temperature (15-25°C):

48 Hours

•   Refrigerated Temperature (2-8°C):

7 Days

•   Freezer Temperature (-20°C):

30 Days

Transport Temperature:

Transport specimen at 2°C – 8 °C (with cold packs)

Rejection Criteria:
  • Hemolyzed specimen
  • Markedly lipemic specimen
  • Exceeded sample stability requirement
  • Quantity not sufficient
  • Improperly labeled specimen
  • Improper collection tube used
Running Day:

Batch running

Cut Off Time:

Monday, 12:00 PM

 

TAT/Releasing of Results:

2 weeks after cut-off (excluding saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Available upon request

Limitations/Interferences:Not Applicable
Frequently Asked Questions (FAQs):Not Applicable
Related Words/Test:Not Applicable

 

Test:DeoxyPyridinDinolin(EIA)
Other Test Request Name:
  • DPD
  • Cross links
  • Lysyl Pyridinum
  • Pyridinolines
  • DeoxyPyridinDinolin - Urine
  •  
Test Composition:

Not Applicable

Intended Use:

There are two major cross linking molecules-pyridinoline and deoxypyridinoline (DPD) which play a role in determining the characteristics of collagen.

Methodology:

Enzyme Immunoassay (EIA)

Laboratory Section:

Special Test

Special Instructions/Patient Preparations:

No patient preparation necessary.

Collection/Sample Container:

Leak proof clean container

Specimen and Volume Requirement
Note:Follow tube manufacturer recommendation.
:

100 mL Random Urine

Alternative Specimen and Volume Requirement:

Not Applicable

Specimen Stability  
•   Room Temperature (15-25°C):

24 Hours

•   Refrigerated Temperature (2-8°C):

5 Days

•   Freezer Temperature (-20°C):

28 Days

Transport Temperature:

Transport specimen at 2 – 8 °C (with cold packs)

Rejection Criteria:
  • Quality Not Sufficient
  • Received room temperature
  • Improperly labeled specimen
  • Improper urine collection
Running Day:

Batch Running

Cut Off Time:

Friday, 12:00 PM

TAT/Releasing of Results:

4 weeks after cut-off (excluding Saturdays, Sundays and Holidays)

Reference Interval/Result Interpretation:

Not Applicable

Limitations/Interferences:

None Specified

Frequently Asked Questions (FAQs):

Not Applicable

Related Words/Test:

Estrogen deficiency, diseases that have high bone turnover rates